Thiosulfate Sulfurtransferase (Rhodanese) (TST) (Middle Region) antibody

Details for Product No. ABIN310285
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Antigen
Synonyms cysA, SCD66.01, SCD84.31, An12g01520, SPCP25A2.01c, AO090010000212, RHODAN, RDS, Rhodanese
Epitope
Middle Region
(2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human, Chicken
(9), (3), (3), (1)
Host
Rabbit
(8), (1)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(9), (4), (4), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN310285
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Immunogen Synthetic peptide directed towards the middle region of human TST
Sequence GEHLGSFYAP RVWWMFRVFG HRTVSVLNGG FRNWLKEGHP VTSEPSRPEP
Predicted Reactivity Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 90 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against TST. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name TST
Background TST is a mitochondrial matrix enzyme that is encoded by the nucleus. It may play roles in cyanide detoxification, the formation of iron-sulfur proteins, and the modification of sulfur-containing enzymes. The product contains two highly conservative domains (rhodanese homology domains), suggesting these domains have a common evolutionary origin.The product of this gene is a mitochondrial matrix enzyme that is encoded by the nucleus. It may play roles in cyanide detoxification, the formation of iron-sulfur proteins, and the modification of sulfur-containing enzymes. The gene product contains two highly conservative domains (rhodanese homology domains), suggesting these domains have a common evolutionary origin. Additional Information IHC Information: Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) IHC Information: Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Molecular Weight 33 kDa
Gene ID 7263
NCBI Accession NP_003303, NM_003312
UniProt Q16762
Research Area Signaling, Metabolism, Organelles
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 297 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Thiosulfate Sulfurtransferase (Rhodanese) (TST) (Middle Region) antibody anti-Thiosulfate Sulfurtransferase (Rhodanese) (TST) (Middle Region) antibody
anti-Thiosulfate Sulfurtransferase (Rhodanese) (TST) (Middle Region) antibody (2) anti-Thiosulfate Sulfurtransferase (Rhodanese) (TST) (Middle Region) antibody (Image 2)
anti-Thiosulfate Sulfurtransferase (Rhodanese) (TST) (Middle Region) antibody (3) anti-Thiosulfate Sulfurtransferase (Rhodanese) (TST) (Middle Region) antibody (Image 3)
Background publications Matthies, Nimtz, Leimkühler: "Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry." in: Biochemistry, Vol. 44, Issue 21, pp. 7912-20, 2005 (PubMed).

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