Autocrine Motility Factor Receptor (AMFR) (C-Term) antibody

Details for Product No. ABIN310408
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Antigen
Synonyms gp78, rnf45, wu:fi06e06, wu:fi37e05, zgc:63893, GP78, RNF45
Epitope
C-Term
(11), (8), (7), (7), (6), (3), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Zebrafish (Danio rerio), Xenopus laevis, Human
(51), (21), (16), (13), (12), (12)
Host
Rabbit
(50), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(41), (24), (18), (10), (9), (8), (5), (3), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN310408
229.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human AMFR
Sequence FGEVEVEPSE VEDFEARGSR FSKSADERQR MLVQRKDELL QQARKRFLNK
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against AMFR. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name AMFR
Background Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).
Molecular Weight 53 kDa
Gene ID 267
NCBI Accession NM_013446
UniProt Q6PGR1
Research Area Cancer, Proteolysis / Ubiquitin
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 482 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Autocrine Motility Factor Receptor (AMFR) (C-Term) antibody WB Suggested Anti-AMFR Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysate
Background publications Lehner, Sanderson: "A protein interaction framework for human mRNA degradation." in: Genome research, Vol. 14, Issue 7, pp. 1315-23, 2004 (PubMed).

Validation Images
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