MTA2 antibody (C-Term)

Catalog No. ABIN310489

This Rabbit Polyclonal antibody specifically detects MTA2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Goat, Guinea Pig and Pigand has been mentioned in 1 publication.

Quick Overview for MTA2 antibody (C-Term) (ABIN310489)

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Goat, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MTA2 Antibody

Binding Specificity: C-Term

Sequence: ALTHLEMRRA ARRPNLPLKV KPTLIAVRPP VPLPAPSHPA STNEPIVLED

Predicted Reactivity: Cow: 88%, Dog: 94%, Goat: 88%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 94%, Pig: 94%, Rabbit: 100%, Rat: 94%

Characteristics: This is a rabbit polyclonal antibody against MTA2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MTA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MTA2 antibody (ABIN310489)

Schiene-Fischer, Yu: "Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases." in: FEBS letters, Vol. 495, Issue 1-2, pp. 1-6, (2001) (PubMed).

Target Details for MTA2

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Alternative Name: MTA2

Background: MTA2 modulates the enzymatic activity of the histone deacetylase core complex.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. This gene is found to be deleted in Williams syndrome.
Alias Symbols: DKFZp686F2281, MTA1L1, PID
Protein Interaction Partner: vpr, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, ZBTB16, UBC, RARA, ZBTB1, RNF2, GPHN, HNRNPR, TRIM28, PPP4R1, ROCK2, SPAG9, POLR2C, POLR2A, MAP4, RPP25, LSM8, GET4, LARP7, CD2AP, NR3C1, MTOR, EHBP1L1, RABEP2, BRCC3, SMEK1, ZGPAT, HDAC1, HDAC2, CSNK1E, MTA3, UBE3
Protein Size: 327

Molecular Weight: 36 kDa

Gene ID: 9219

NCBI Accession: NM_003602, NP_004730

UniProt: O94776

Pathways: Chromatin Binding