Podoplanin (PDPN) antibody
| Antigen |
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| Synonyms |
T1A, GP36, GP40, Gp38, OTS8, T1A-2, AGGRUS, HT1A-1, PA2.26, T1a, OTS-8, T1alpha, RANDAM-2, E11, RTI40, T1-alpha, PDPN |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Conjugate
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Alexa Fluor (8), PE (7), Biotin (4), FITC (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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 Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB) (52), Flow Cytometry (FACS) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (28), Immunohistochemistry (IHC) (26), Immunofluorescence (IF) (22), Immunoprecipitation (IP) (19), ELISA (16), Immunohistochemistry (Fixed) (IHC (fx)) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Fluorescence Microscopy (FM) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Intracellular Staining (IS) (1)
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| Catalog no. |
ABIN310607 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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Podoplanin
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Gene ID
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PDPN
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UniProt
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A1A5S2
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Immunogen
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The immunogen for anti-PDPN antibody: synthetic peptide directed towards the N terminal of human PDPN
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Sequence
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EGASTGQPEDDTETTGLEGGVAMPGAEDDVVTPGTSEDRY KSGLTTLVAT
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Cross-Reactivity
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Human
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-PDPN antibody concentration is 1 mg/ml.
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Description
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PDPN is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury.This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Characteristics
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Antigen Size: 238 amino acids
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Molecular Weight
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25kDa
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Application Notes
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WB Suggested Anti-PDPN Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Wicki, Lehembre, Wick et al.: "Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton." in: Cancer cell, Vol. 9, Issue 4, pp. 261-72, 2006 (PubMed).
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Alternatives for antigen "Podoplanin (PDPN)", type "Antibodies"
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Hosts
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Rabbit (40), Mouse (30), Rat (20), Hamster (8), Syrian Hamster (4), Goat (3), Sheep (1)
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Reactivities
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Human (58), Mouse (Murine) (39), Rat (Rattus) (21), Dog (Canine) (1)
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Applications
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Western Blotting (WB) (52), Flow Cytometry (FACS) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (28), Immunohistochemistry (IHC) (26), Immunofluorescence (IF) (22), Immunoprecipitation (IP) (19), ELISA (16), Immunohistochemistry (Fixed) (IHC (fx)) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Fluorescence Microscopy (FM) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Intracellular Staining (IS) (1)
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Conjugates
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Alexa Fluor (8), PE (7), Biotin (4), FITC (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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AA 38-51 (9), N-Term (4), AA 1-206 (3), Internal Region (2), C-Term (1), Extracellular Domain (1)
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2013 BioMed Central Research Awards
