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phosphodiesterase 9A (PDE9A) antibody

Antigen

phosphodiesterase 9A (PDE9A)

Synonyms HSPDE9A2, PDE9A1, PDE9A, MGC116558, Pde9a, LOC799942
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)

Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1 reference available
Catalog no. ABIN310727
Quantity 50 µg
Price Product not available in this region.
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Additional Information

Alternative name PDE9A
Description PDE9A catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides.The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. Keywords: PDE9A, NM_001001581, NP_001001581, O76083-13

Application Details

Application Notes ELISA titre: 1:312500 . Western Blotting: Suggested dilution at 1.0 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Research Area Signaling, Enzymes, Metabolism
Restrictions For Research Use only

Publications

Publications Huai, Wang, Zhang et al.: "Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 26, pp. 9624-9, 2004 (PubMed).