APOBEC3B antibody (N-Term)

Catalog No. ABIN310774

This Rabbit Polyclonal antibody specifically detects APOBEC3B in WB. It exhibits reactivity toward Human, Rat, Cow, Horse, Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for APOBEC3B antibody (N-Term) (ABIN310774)

Target: APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))

Reactivity: Human, Rat, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APOBEC3B Antibody

Binding Specificity: N-Term

Purpose: APOBEC3B Antibody - N-terminal region

Sequence: NQLPAYKCFQ ITWFVSWTPC PDCVAKLAEF LSEHPNVTLT ISAARLYYYW

Predicted Reactivity: Cow: 82%, Horse: 91%, Human: 100%, Pig: 92%, Rabbit: 82%, Rat: 91%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against APOBEC3B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APOBEC3B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094805

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for APOBEC3B

Target: APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))

Alternative Name: APOBEC3B

Background:

Background Information: APOBEC3B is a member of the cytidine deaminase family. It is thought that these proteins may be RNA editing enzymes and have roles in growth or cell cycle control.This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.

Gene Name: Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B

Alternative Symbols: A3B, ARP4, ARCD3, PHRBNL, APOBEC1L, bK150C2.2, DJ742C19.2

Protein Name: Probable DNA dC->dU-editing enzyme APOBEC-3B

Molecular Weight: 46kDa

Gene ID: 9582

NCBI Accession: NP_004891

UniProt: Q9UH17