PIGW antibody (Middle Region)

Catalog No. ABIN311149

Product Details anti-PIGW Antibody

Target: PIGW (Phosphatidylinositol Glycan W (PIGW))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGW antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IALGITVLYQ LALDFTSLKR LILYGTDGSG TRVGLLNANR EGIISTLGYV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PIGW. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PIGW

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 504 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIGW

Target: PIGW (Phosphatidylinositol Glycan W (PIGW))

Alternative Name: PIGW (PIGW Products)

Synonyms: Gwt1 antibody, PIG-W antibody, 2610044A17Rik antibody, phosphatidylinositol glycan anchor biosynthesis class W antibody, phosphatidylinositol glycan anchor biosynthesis, class W antibody, PIGW antibody, Pigw antibody

Background: Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-430 AK094752.1 1-430 431-1570 AB097818.1 376-1515 1571-2255 AK094752.1 1571-2255
Alias Symbols: FLJ37433, Gwt1
Protein Interaction Partner: UBC,
Protein Size: 504

Molecular Weight: 57 kDa

Gene ID: 284098

NCBI Accession: NM_178517, NP_848612

UniProt: Q7Z7B1

Pathways: Inositol Metabolic Process