DYNC1I1 antibody (N-Term)

Catalog No. ABIN311487

This anti-DYNC1I1 antibody is a Rabbit Polyclonal antibody detecting DYNC1I1 in WB. Suitable for Human, Rat, Mouse, Guinea Pig, Horse, Rabbit, Dog and Cow.

Quick Overview for DYNC1I1 antibody (N-Term) (ABIN311487)

Target: DYNC1I1 (Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1))

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Rabbit, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1I1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DYNC1I1 Antibody

Binding Specificity: N-Term

Sequence: IREEKKRKEE ERKKKEADMQ QKKEPVQDDS DLDRKRRETE ALLQSIGISP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DYNC1I1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DYNC1I1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 645 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DYNC1I1

Target: DYNC1I1 (Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1))

Alternative Name: DYNC1I1

Background: DYNC1I1 belongs to the dynein intermediate chain family. It contains 7 WD repeats. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. DYNC1I1 may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Alias Symbols: DNCI1, DNCIC1
Protein Interaction Partner: AMBRA1, TRIM58, BECN1, DYNLL1, UBC, Bicd2, DYNC1LI1, DCTN2, DYNC1H1, DCTN1, Ccdc64b, Ccdc64, GNB1, KLC3, EMILIN1, TUBB3, PAFAH1B1, KCNA5, CUL3, KIAA0368, DNM2, CADM4, RUNDC3B, FAM110A, FAM83D, C2orf44, TAOK1, NAGK, KAT7, NUDT21, TK1, SMN1, RAP1GAP, PIN1,
Protein Size: 645

Molecular Weight: 73 kDa

Gene ID: 1780

NCBI Accession: NM_004411, NP_004402

UniProt: O14576