anti-ALDH1L1 antibody (Aldehyde Dehydrogenase 1 Family, Member L1) (Middle Region)

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Antigen
Synonyms FDH, fthfd, ALDH1L1, FTHFD, DKFZp469C068, 10-FTHFDH, 10-fTHF, 1810048F20Rik, Fthfd, Neut2
Epitope
Middle Region
(10), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(82), (20), (17), (8), (4), (4), (1)
Host
Rabbit
(66), (23)
Clonality
Polyclonal
Conjugate
This ALDH1L1 antibody is un-conjugated
(2), (2), (1)
Application
Western Blotting (WB)
(62), (32), (29), (26), (23), (23), (13), (9), (4), (2), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human ALDH1L1
Blocking Peptide Blocking peptide for this product available: Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) peptide (ABIN973103)
Sequence LTLKAGIPKG VVNVLPGSGS LVGQRLSDHP DVRKIGFTGS TEVGKHIMKS
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against ALDH1L1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ALDH1L1 (ALDH1L1 Antibody Abstract)
Background ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Molecular Weight 99 kDa
Gene ID 10840
NCBI Accession NP_036322, NM_012190
UniProt O75891
Research Area Cancer, Cell Cycle, Metabolism, Apoptosis/Necrosis, Glia marker
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 902 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-ALDH1L1 antibody (Aldehyde Dehydrogenase 1 Family, Member L1) (Middle Region) (ABIN311502) WB Suggested Anti-ALDH1L1 Antibody Titration: 0.2-1 ug/ml
Positive Contr...
Background publications Lee, Lan, Kricker et al.: "One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia." in: Human genetics, Vol. 122, Issue 5, pp. 525-33, 2007 (PubMed).

Catalog No. ABIN311502
$289.00
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