Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) antibody
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| Synonyms |
FTHFD, DKFZp781N0997, Fthfd, MGC105431, 1810048F20Rik, fthfd, aldh1l1, DKFZP469I2021, ALDH1L1, MGC179366, DKFZp469C068 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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| Catalog no. |
ABIN311502 |
| Quantity |
50 µg |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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ALDH1L1 / FTHFD
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Gene ID
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ALDH1L1
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UniProt
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O75891
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Immunogen
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The immunogen for anti-ALDH1L1 antibody: synthetic peptide directed towards the middle region of human ALDH1L1
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Sequence
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LTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGS TEVGKHIMKS
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Cross-Reactivity
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Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-ALDH1L1 antibody concentration is 1 mg/ml.
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Description
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ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
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Characteristics
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Antigen Size: 902 amino acids
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Molecular Weight
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99kDa
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Application Notes
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WB Suggested Anti-ALDH1L1 Antibody Titration: 0.2-1 ug/ml Positive Control: Human Liver.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Lee, Lan, Kricker et al.: "One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia." in: Human genetics, Vol. 122, Issue 5, pp. 525-33, 2007 (PubMed).
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Alternatives for antigen "Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1)", type "Antibodies"
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Hosts
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Rabbit (26), Mouse (18)
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Reactivities
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Human (37), Dog (Canine) (23), Mouse (Murine) (22), Rat (Rattus) (20), Horse (Equine) (18), Pig (Porcine) (18), Monkey (1)
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Applications
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Western Blotting (WB) (26), Immunofluorescence (IF) (25), ELISA (12), Immunohistochemistry (IHC) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Flow Cytometry (FACS) (7), Immunostaining (ISt) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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C-Term (6), Internal Region (1)
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