ZCCHC12 antibody (N-Term)

Catalog No. ABIN311555

The Rabbit Polyclonal anti-ZCCHC12 antibody has been validated for WB. It is suitable to detect ZCCHC12 in samples from Human, Mouse, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse and Pig.

Quick Overview for ZCCHC12 antibody (N-Term) (ABIN311555)

Target: ZCCHC12 (Zinc Finger, CCHC Domain Containing 12 (ZCCHC12))

Reactivity: Human, Mouse, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZCCHC12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZCCHC12 Antibody

Binding Specificity: N-Term

Sequence: AREVMRVLQA TNPNLSVADF LRAMKLVFGE SESSVTAHGK FFNTLQAQGE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ZCCHC12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZCCHC12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 402 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZCCHC12

Target: ZCCHC12 (Zinc Finger, CCHC Domain Containing 12 (ZCCHC12))

Alternative Name: ZCCHC12

Background: ZCCHC12 contains 1 CCHC-type zinc finger. ZCCHC12 is the transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.
Alias Symbols: FLJ16123, SIZN, SIZN1, PNMA7A
Protein Interaction Partner: PNMA1, SUMO1, TFCP2, MAGEA11, SUMO2, APP, SMAD1, CREBBP, UBC, APPBP2,
Protein Size: 402

Molecular Weight: 45 kDa

Gene ID: 170261

NCBI Accession: NM_173798, NP_776159

UniProt: Q6PEW1