TNP1 antibody (N-Term)

Catalog No. ABIN311601

The Rabbit Polyclonal anti-TNP1 antibody (ABIN311601) specifically detects TNP1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow, Guinea Pig and Sheep samples.

Quick Overview for TNP1 antibody (N-Term) (ABIN311601)

Target: TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNP1 Antibody

Binding Specificity: N-Term

Purpose: TNP1 Antibody - N-terminal region

Sequence: MSTSRKLKSH GMRRSKSRSP HKGVKRGGSK RKYRKGNLKS RKRGDDANRN

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against TNP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114308

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TNP1

Target: TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))

Alternative Name: TNP1

Background:

Background Information: TNP1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines.Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880, PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM]. Sequence Note: removed 4 bases from the 5' end that did not align to the reference genome assembly. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Transition protein 1 (during histone to protamine replacement)

Alternative Symbols: TP1

Protein Name: Spermatid nuclear transition protein 1

Molecular Weight: 6kDa

Gene ID: 7141

NCBI Accession: NP_003275

UniProt: P09430