STAG3 antibody (Middle Region)

Catalog No. ABIN311619

The Rabbit Polyclonal anti-STAG3 antibody (ABIN311619) specifically detects STAG3 in WB. The antibody is reactive with Human and Zebrafish (Danio rerio) samples.

Quick Overview for STAG3 antibody (Middle Region) (ABIN311619)

Target: STAG3 (Stromal Antigen 3 (STAG3))

Reactivity: Human, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAG3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STAG3 Antibody

Binding Specificity: Middle Region

Sequence: VPHQVILPAL TLVYFSILWT LTHISKSDAS QKQLSSLRDR MVAFCELCQS

Predicted Reactivity: Human: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against STAG3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STAG3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1225 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAG3

Target: STAG3 (Stromal Antigen 3 (STAG3))

Alternative Name: STAG3

Background: STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Alias Symbols: -
Protein Interaction Partner: SMC3, SMC1A,
Protein Size: 1225

Molecular Weight: 135 kDa

Gene ID: 10734

NCBI Accession: NM_012447, NP_036579

UniProt: Q9UJ98