Tetratricopeptide Repeat Domain 12 (TTC12) (C-Term) antibody

Details for Product No. ABIN311633
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Antigen
Synonyms TPARM, E330017O07Rik
Epitope
C-Term
(3), (2)
Reactivity
Rat (Rattus), Mouse (Murine), Cow (Bovine), Human
(5), (1)
Host
Rabbit
(3), (2)
Clonality
Polyclonal
Application
Western Blotting (WB)
(5), (3)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN311633
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human TTC12
Sequence MNLCLQAPFV SEVWAVEVSR RCLSLLNSQD GGILTRAAGV LSRTLSSSLK
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Rabbit : 100 %, Rat : 100 %, Mouse : 90 %, Pig : 90 %
Characteristics This is a rabbit polyclonal antibody against TTC12. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TTC12
Background TTC12 contains 3 TPR repeats. Hypermethylation of TTC12 gene may play a role in acute lymphoblastic leukemia. Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.
Molecular Weight 81 kDa
Gene ID 54970
NCBI Accession NM_017868, NP_060338
UniProt B0YJB4
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 732 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Tetratricopeptide Repeat Domain 12 (TTC12) (C-Term) antibody WB Suggested Anti-TTC12 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Muscle
Background publications Yang, Kranzler, Zhao et al.: "Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples." in: Human molecular genetics, Vol. 16, Issue 23, pp. 2844-53, 2007 (PubMed).

Validation Images
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