CCL13 antibody (Middle Region)

Catalog No. ABIN311734

This Rabbit Polyclonal antibody specifically detects CCL13 in WB. It exhibits reactivity toward Human.

Quick Overview for CCL13 antibody (Middle Region) (ABIN311734)

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCL13 Antibody

Binding Specificity: Middle Region

Purpose: CCL13 Antibody - middle region

Sequence: KSYVITTSRC PQKAVIFRTK LGKEICADPK EKWVQNYMKH LGRKAHTLKT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CCL13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCL13

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCL13

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Alternative Name: CCL13

Background:

Background Information: Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL13 displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.

Gene Name: Chemokine (C-C motif) ligand 13

Alternative Symbols: NCC1, CKb10, MCP-4, NCC-1, SCYL1, SCYA13

Protein Name: C-C motif chemokine 13

Molecular Weight: 11kDa

Gene ID: 6357

NCBI Accession: NP_005399

UniProt: Q99616

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, The Global Phosphorylation Landscape of SARS-CoV-2 Infection