CD137 antibody

Catalog No. ABIN181132

This Rat Monoclonal antibody specifically detects CD137 in FACS, Func and EIA. It exhibits reactivity toward Human and Monkey.

Quick Overview for CD137 antibody (ABIN181132)

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reactivity: Human, Monkey

Host: Rat

Clonality: Monoclonal

Conjugate: This CD137 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: JG1-6A

Product Details anti-CD137 Antibody

Specificity: This antibody recognises CD137, an 83 kDa type I integral membrane protein, otherwise known as 4-1BB.

Characteristics: Synonyms: 4-1BB ligand receptor, 4-1BB homolog, ILA, CDw137, Tumor necrosis factor receptorsuperfamily member 9, T-cell antigen 4-1BB homolog, T-cell antigen ILA

Purification: Affinity Chromatography on Protein G

Immunogen: Recombinant Human CD137-Fc. Lymph node cells from immunised Lou rat were fused withcells of the mouse NS-1 myeloma cell line. Genename: CD137

Isotype: IgG2a

Application Details

Application Notes: ELISA. Flow Cytometry. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD137

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Alternative Name: CD137 / TNFRSF9

Background: The CD137 Molecule is primarily expressed on activated T-cells. It is a costimulatory member of the tumour necrosis receptor family and is reported to regulate T-cell activation and proliferation.Synonyms: 4-1BB homolog, 4-1BB ligand receptor, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, Tumor necrosis factor receptor superfamily member 9

Gene ID: 3604

UniProt: Q07011

Pathways: Cancer Immune Checkpoints