PPP1CA antibody (AA 30-299)

Catalog No. ABIN316597

This Mouse Monoclonal antibody specifically detects PPP1CA in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for PPP1CA antibody (AA 30-299) (ABIN316597)

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPP1CA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 4G3

Product Details anti-PPP1CA Antibody

Binding Specificity: AA 30-299

Specificity: This antibody is specific for PPP1CA.

Characteristics: Synonyms: PPP1A, PP-1A, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human PPP1CA (30-299aa) purified from E. coli

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western blot (1/500-1/2,000). Immunohistochemistry on Paraffin Sections (5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PPP1CA

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Alternative Name: PPP1CA

Background: Protein phosphatase 1, catalytic subunit, alpha isoform, also known as PPP1CA, is one of the three catalytic subunits of protein phosphatase 1. The protein is highly conserved in eukaryotic cells and play a role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinaseII. It is participate in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis and apoptosis.Synonyms: PP-1A, PPP1A, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Gene ID: 5499

UniProt: P62136

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism