EMR3 antibody

Catalog No. ABIN317634

The Rabbit Polyclonal anti-EMR3 antibody (ABIN317634) specifically detects EMR3 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for EMR3 antibody (ABIN317634)

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-EMR3 Antibody

Specificity: This antibody detects endogenous levels of EMR3 protein.(region surrounding Tyr652)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EMR3

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Alternative Name: EMR3

Background: EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.Synonyms: EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3

Gene ID: 84658

NCBI Accession: NP_115960

UniProt: Q9BY15