EMR2 antibody

Catalog No. ABIN317649

The Rabbit Polyclonal anti-EMR2 antibody (ABIN317649) specifically detects EMR2 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for EMR2 antibody (ABIN317649)

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-EMR2 Antibody

Specificity: This antibody detects endogenous levels of EMR2 protein.(region surrounding Leu160)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EMR2

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Alternative Name: CD312 / EMR2

Background: EMR2 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system, where it has been shown to be restricted specifically to monocytes and granulocytes. Family members are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 3 on chromosome 19. This protein does not interact with the ligand decay accelerating factor for complement, unlike the related CD97 antigen, and indicates that these very closely related proteins likely have nonredundant functions. This gene results in multiple transcripts encoding distinct isoforms. ESTs have been isolated from blood, colon, lymph node, placenta, spleen, testis, and uterus libraries.Synonyms: EGF-like module EMR2, EGF-like module-containing mucin-like hormone receptor-like 2

Gene ID: 30817

NCBI Accession: NP_038475

UniProt: Q9UHX3