GNAL antibody

Catalog No. ABIN317912

The Rabbit Polyclonal anti-GNAL antibody is suitable to detect GNAL in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for GNAL antibody (ABIN317912)

Target: GNAL (Guanine Nucleotide Binding Protein, alpha Stimulating, Olfactory Type (GNAL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GNAL Antibody

Specificity: This antibody detects endogenous levels of G alpha olf protein.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GNAL

Target: GNAL (Guanine Nucleotide Binding Protein, alpha Stimulating, Olfactory Type (GNAL))

Alternative Name: G alpha Protein Olf

Background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP, and most obviously regulate the activity of the best studied effectors. The Gs subfamily of Gα subunits includes two closely related proteins, Gα s and Gα olf, which, respectively, stimulate adenylate cyclase and mediate response to olfactory stimuli.Synonyms: Adenylate cyclase-stimulating G alpha protein olfactory type, GNAL, Guanine nucleotide-binding protein G(olf) subunit alpha

Molecular Weight: approx. 40 kDa

Gene ID: 2774

NCBI Accession: NP_001135811

UniProt: P38405