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Antibodies
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anti-Methamphetamine (M-Amp) antibody
Methamphetamine (M-Amp) antibody
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| Clonality |
Polyclonal |
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Host
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Application
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| Catalog no. |
ABIN318601 |
| Quantity |
1 ml (5.0 mg/ml) (Variants) |
| Price |
290.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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Methamphetamine
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Immunogen
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Para-amino-metamphetamine conjugated to keyhole limpet hemocyanin
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH isa potent central nervous system stimulant with additional peripheral sympathomimeticeffects. METH and AMPH have been used clinically in the treatment of obesity, minimalbrain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjectedto widespread abuse. METH is an indirect agonists. It causes the release of newlysynthesized norepinephrine and dopamine and it blocks the re uptake of thesetransmitters from the synapse. This can lead to an increase in the concentration ofcatecholamines in the synapse as well as an overall increase in catecholaminergic activityin the brain. The mechanism of METH induced neurotoxicity for all monoaminergic celltypes may lie primarily with the dopaminergic system in the striatum. It may also lie withthe interaction between METH induced release of dopamine and its ability to inhibitmonoamine oxidase.
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Specificity
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This antibody is specific for methamphetamine.
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Application Notes
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ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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5.0 mg/ml
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Purification
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Purified
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Buffer
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Phosphate buffered saline containing 0.09% Sodium Azide (NaN3)
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
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Research Area
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Drugs
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Restrictions
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For Research Use only
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Alternatives for antigen "Methamphetamine (M-Amp)", type "Antibodies"
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Hosts
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Mouse (26), Sheep (26), Rabbit (23)
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Reactivities
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Cow (Bovine) (1), Horse (Equine) (1), Human (1), Mouse (Murine) (1), Pig (Porcine) (1), Rat (Rattus) (1), Sheep (Ovine) (1)
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Applications
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ELISA (24), Immunofluorescence (IF) (23), Flow Cytometry (FACS) (18), Enzyme Immunoassay (EIA) (12), Western Blotting (WB) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), To be determined by user (TBD) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Biotin (1), Colloidal Gold (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
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Alternatives 
