Ectodysplasin A2 Receptor antibody

Catalog No. ABIN318757

This Rabbit Polyclonal antibody specifically detects Ectodysplasin A2 Receptor in WB. It exhibits reactivity toward Human.

Quick Overview for Ectodysplasin A2 Receptor antibody (ABIN318757)

Target: Ectodysplasin A2 Receptor (EDA2R)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A2 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ectodysplasin A2 Receptor Antibody

Specificity: This antibody detects human X-linked ectodermal dysplasia receptor (XEDAR).

Purification: Purified

Immunogen: Recombinant human XEDAR.

Isotype: IgG

Application Details

Application Notes: Western Blot: 0.5 - 2.0g/mL, detects a band of approximately 33 kDa in 293 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for Ectodysplasin A2 Receptor

Target: Ectodysplasin A2 Receptor (EDA2R)

Alternative Name: EDA2R / TNFRSF27

Background: XEDAR is a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist, XEDAR-s and XEDAR-L, produced by alternative splicing.Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR

Gene ID: 60401

NCBI Accession: NP_001186616

UniProt: Q9HAV5