BAFF antibody (AA 254-269)

Catalog No. ABIN319035

The Rabbit Polyclonal anti-BAFF antibody (ABIN319035) specifically detects BAFF in WB and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BAFF antibody (AA 254-269) (ABIN319035)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAFF antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-BAFF Antibody

Binding Specificity: AA 254-269

Specificity: This antibody recognises CD257 (also known as BLyS, BAFF, TALL-1 and THANK).

Purification: Purified

Immunogen: Peptide corresponding to amino acids 254-269 of human CD257 (BAFF).

Isotype: IgG

Application Details

Application Notes: Western Blot: 0.25g/mL - 1g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Alternative Name: CD257 / BAFF

Background: CD257 is a novel member of the tumor necrosis factor (TNF) superfamily. CD257 and its receptor TACI/BCMA are involved in the development of autoimmune diseases. CD257 has been shown to activate NFkB and JNK (c-jun N-terminal kinase) and induce apoptosis.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4

Gene ID: 10673

NCBI Accession: NP_001139117

UniProt: Q9Y275

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response