CD35 antibody (PE)

Catalog No. ABIN319721

The Mouse Monoclonal anti-CD35 antibody is suitable to detect CD35 in samples from Human and Monkey. It has been validated for FACS.

Quick Overview for CD35 antibody (PE) (ABIN319721)

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD35 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: E11

Product Details anti-CD35 Antibody (PE)

Purification: Affinity chromatography on Protein A.

Immunogen: Human acute monocytic leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative, 1 % BSA as stabilizer and Inert Bulking Reagent.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for CD35

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Alternative Name: CD35 / C3BR

Background: CD35 is a single chain cell surface glycoprotein which exists in four allotypic forms (A,B,C,D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement.Synonyms: C3b/C4b receptor, CR1, Complement receptor type 1

Gene ID: 9606

UniProt: P17927

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity