KIR2DL3 antibody

Catalog No. ABIN320355

The Mouse Monoclonal anti-KIR2DL3 antibody (Clone 190IIC311) (ABIN320355) specifically detects KIR2DL3 in WB, FACS and EIA. The antibody is reactive with Human samples.

Quick Overview for KIR2DL3 antibody (ABIN320355)

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIR2DL3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: 190IIC311

Product Details anti-KIR2DL3 Antibody

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human KIR2DL3

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry (5-10g/1x10^6). ELISA (1:1,000 when tested against the immunizing protein). Western blot (1 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product is routinely tested on peripheral blood mononuclear cells(PBMCs) or natural killer(NK) cells. The histogram is an example Profile of NK cells analyzed by flow cytometry of the expected reactivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for KIR2DL3

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Alternative Name: CD158b / KIR2DL3

Background: KIR2DL3 is a member of the killer cell immunoglobulin-like receptor(KIR) family. The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells which they are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities.Synonyms: KIRCL23, Killer cell immunoglobulin-like receptor 2DL3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2

UniProt: P43628

Pathways: Cancer Immune Checkpoints