KIR2DL3 antibody (AA 42-140)

Catalog No. ABIN748448

There is 1 publication for this product available. The Rabbit Polyclonal anti-KIR2DL3 antibody is suitable to detect KIR2DL3 in samples from Human. It has been validated for ELISA, ICC, IF (p), IF (cc), IHC (fro) and IHC (p).

Quick Overview for KIR2DL3 antibody (AA 42-140) (ABIN748448)

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIR2DL3 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KIR2DL3 Antibody

Binding Specificity: AA 42-140

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD158b2/KIR2DL3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-KIR2DL3 antibody (ABIN748448)

Mozer-Lisewska, Mania, Kowala-Piaskowska, Kluk, Samara, Pauli, ?eromski: "Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers." in: Archivum immunologiae et therapiae experimentalis, Vol. 62, Issue 2, pp. 153-60, (2014) (PubMed).

Target Details for KIR2DL3

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Alternative Name: KIR2DL3

Background:

Synonyms: p58, NKAT, GL183, NKAT2, CD158b, NKAT2A, NKAT2B, CD158B2, KIR-K7b, KIR-K7c, KIR2DS5, KIRCL23, KIR-23GB, Killer cell immunoglobulin-like receptor 2DL3, CD158 antigen-like family member B2, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, Natural killer-associated transcript 2, NKAT-2, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I-specific NK receptor, KIR2DL3

Background: Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Gene ID: 3804

UniProt: P43628

Pathways: Cancer Immune Checkpoints