TCF7L2 antibody (AA 251-300)

Catalog No. ABIN6737719

This Rabbit Polyclonal antibody specifically detects TCF7L2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Horse and Rabbit.

Quick Overview for TCF7L2 antibody (AA 251-300) (ABIN6737719)

Target: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Reactivity: Human, Mouse, Rat, Cow, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF7L2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TCF7L2 Antibody

Binding Specificity: AA 251-300

Specificity: Human TCF7L2

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig, Chicken, Zebrafish (92%) Xenopus (84%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa251-300 of human TCF7L2 (Q6FHW4, NP_110383). Percent identity by BLAST analysis: Human, Chimpanzee, Mouse, Rat, Bovine, Rabbit, Horse, Pig (100%), Gibbon, Monkey, Galago, Marmoset, Elephant, Dog, Bat, Opossum, Guinea pig, Zebra finch, Chicken, Platypus, Xenopus, Zebrafish (92%), Turkey (84%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB

Usage: ELISA titer using peptide based assay: 1:2500. Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for TCF7L2

Target: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Alternative Name: TCF7L2 / TCG4

Background: Name/Gene ID: TCF7L2
Family: Transcription factor

Synonyms: TCF7L2, HMG box transcription factor 4, HTCF-4, T-cell factor-4 variant X2, T-cell factor 4, Transcription factor 7-like 2, TCF-4

Gene ID: 6934

NCBI Accession: NP_110383

UniProt: Q9NQB0

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus