Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody

Antigen: Chemokine (C-X-C Motif) Receptor 3 (CXCR3)

Synonyms: GPR9, MigR, CD182, CD183, Mig-R, CKR-L2, CMKAR3, IP10-R, Cd183, Cmkar3, CXCR3, cxcr3

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN334381

Additional Information

Alternative name: CXCR3 / GPR9

Gene ID: 2833, 12766 (mouse), 84475 (rat)

Immunogen: C-RRDSSWSETSEA

Description: All names and symbols: CXCR3, chemokine (C-X-C motif) receptor 3, HGNC:4540, CD183, CKR-L2, CMKAR3, GPR9, IP10, IP10-R, Mig-R, MigR, G protein-coupled receptor 9, IP10 receptor, Mig receptor, chemokine (C-X-C) receptor 3. Official Symbol: CXCR3. RefSeq number(s): NP_001495.1

Specificity: Human, Mouse, Rat

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Preliminary experiments gave an approx 50-55kDa band in lysates of human thymus, kidney and placenta, and of cell line HeLa after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 40.7kDa according to NP_001495.1. The 50-55kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Martini, Zulian, Calabrese et al.: "CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritis." in: Arthritis research & therapy, Vol. 7, Issue 2, pp. R241-9, 2005 (PubMed).