FOXP2 antibody (Internal Region)

Catalog No. ABIN334400

The Goat Polyclonal anti-FOXP2 antibody has been validated for ELISA and IHC. It is suitable to detect FOXP2 in samples from Human. There is 1 publication available.

Quick Overview for FOXP2 antibody (Internal Region) (ABIN334400)

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This FOXP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-FOXP2 Antibody

Binding Specificity: Internal Region

Purpose: FOXP2 (internal)

Sequence: DEVEYQKRRS QKIT

Specificity: This antibody is expected to recognize isoform I (NP_055306.1), isoform II (NP_683696.2), isoform IV (NP_683698.2) and isoform V (NP_001166237.1).

Cross-Reactivity: Cat, Cow, Dog, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-DEVEYQKRRSQKIT, from the internal region of the protein sequence according to NP_055306.1, NP_683696.2, NP_683697.2, NP_683698.2, NP_001166237.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Prostate and Placenta. Recommended concentration: 2.5 μg/mL.

Western Blot: Preliminary testing showed an approx 90 kDa band in Human Cerebellum lysate and an approx 75 kDa band in Rat Brain lysate after 0.3 μg/mL staining. An additional band of unknown identity was also consistently observed at 28-30 kDa and was succ

Peptide ELISA: antibody detection limit dilution 1:64000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-FOXP2 antibody (ABIN334400)

Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

Target Details for FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Alternative Name: FOXP2

Background: FOXP2, forkhead box P2 , CAGH44, DKFZp686H1726, SPCH1, TNRC10 , CAG repeat protein 44, forkhead/winged-helix transcription factor, speech and language disorder 1, trinucleotide repeat containing 10

Gene ID: 93986, 114142

NCBI Accession: NP_055306, NP_683696, NP_683697, NP_683698, NP_001166237