ABCC8 antibody (C-Term)

Catalog No. ABIN334499

The Goat Polyclonal anti-ABCC8 antibody has been validated for WB and ELISA. It is suitable to detect ABCC8 in samples from Human.

Quick Overview for ABCC8 antibody (C-Term) (ABIN334499)

Target: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ABCC8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-ABCC8 Antibody

Binding Specificity: C-Term

Purpose: SUR1 / ABCC8

Sequence: EFDKPEKLLS RKD

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-EFDKPEKLLSRKD, from the C Terminus of the protein sequence according to NP_000343.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 170 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177 kDa according to NP_000343.2). Recommended concentration: 0.5-1.5 μg/mL. An additional band of unknown identity was also consistently observed at 23 kDa. Thi

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for ABCC8

Target: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Alternative Name: ABCC8

Background: ABCC8, SUR1, ATP-binding cassette, sub-family C (CFTR/MRP), member 8, ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, TNDM2, ATP-binding cassette, sub-family C, member 8, sulfonylurea receptor (hyperinsulinemia)

Gene ID: 6833, 20927, 25559

NCBI Accession: NP_000343

Pathways: Negative Regulation of Hormone Secretion