Did you know that you can buy products from over 140 different suppliers from us?

Keratin 14 (KRT14) antibody

Details for Product No. ABIN335329
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Krt14, KRT14, CK14, ouro2, EBS3, EBS4, K14, NFJ, AI626930, Krt-1.14, Krt1-14, Ka14
Reactivity
Human, Rat (Rattus), Dog (Canine), Pig (Porcine)
(130), (25), (22), (6), (3), (3), (2)
Host
Mouse
(71), (57), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3)
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(83), (76), (45), (30), (26), (20), (16), (15), (2), (2)
Pubmed 7 references available
Quantity 100 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 7 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN335329
396.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen RCK107 is a mouse monoclonal IgG3 antibody derived by fusion of SP2/0-Ag14 mouse myeloma cells with spleen cells from a mouse immunized with a cytoskeletal preparation of TR146 epithelial cells.
Clone RCK107
Isotype IgG1
Specificity Human, rat, canine and swine.
Purification Purified
Alternative Name Cytokeratin 14 / Keratin K14
Background Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Application Notes RCK107 reacts exclusively with cytokeratin 14 which is present in basal cell compartments of stratified and combined epithelia. RCK107 is suitable for immunocytochemistry, immunohistochemistry on frozen sections, flow cytometry and immunoblotting. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
Restrictions For Research Use only
Concentration 1 mg/ml
Storage 4 °C
Supplier Images
anti-Keratin 14 (KRT14) antibody anti-Keratin 14 (KRT14) antibody
anti-Keratin 14 (KRT14) antibody (2) anti-Keratin 14 (KRT14) antibody (Image 2)
General Vos, van den Ingh, de Neijs et al.: "Immunohistochemistry with keratin monoclonal antibodies in canine tissues: urogenital tract, respiratory tract, (neuro-)endocrine tissues, choroid plexus and spinal cord." in: Zentralblatt für Veterinärmedizin. Reihe A, Vol. 39, Issue 10, pp. 721-40, 1993 (PubMed).

Smedts, Ramaekers, Troyanovsky et al.: "Basal-cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia." in: The American journal of pathology, Vol. 140, Issue 3, pp. 601-12, 1992 (PubMed).

Wetzels, Schaafsma, Leigh et al.: "Laminin and type VII collagen distribution in different types of human lung carcinoma: correlation with expression of keratins 14, 16, 17 and 18." in: Histopathology, Vol. 20, Issue 4, pp. 295-303, 1992 (PubMed).

Bauwens, De Groot, Ramaekers et al.: "Expression of intermediate filament proteins in the adult human vestibular labyrinth." in: The Annals of otology, rhinology, and laryngology, Vol. 101, Issue 6, pp. 479-86, 1992 (PubMed).

Smedts, Ramaekers, Troyanovsky et al.: "Keratin expression in cervical cancer." in: The American journal of pathology, Vol. 141, Issue 2, pp. 497-511, 1992 (PubMed).

Wetzels, Kuijpers, Lane et al.: "Basal cell-specific and hyperproliferation-related keratins in human breast cancer." in: The American journal of pathology, Vol. 138, Issue 3, pp. 751-63, 1991 (PubMed).

Meek, Van Elssen, Huijskens et al.: "T cells fail to develop in the human skin-cell explants system; an inconvenient truth." in: BMC immunology, Vol. 12, Issue 1, pp. 17, 2011 (PubMed).

Validation Images
back to top