Calca
Reactivity: Mouse
WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Immunohistochemistry (IHC) 1:50-1:200 using polymer or streptavidin biotin system. For 30 minute at room temperature. The optimum dilution should be determined by the individual lab. General Reference: Holm, R, J Pathology, 158: 213-217,1989 Positive Control: Human thyroid or medulary carcinoma. Cellular Localization: Cytoplasmic.
Restrictions
For Research Use only
Format
Liquid
Buffer
Total immunoglobulin fraction in10 mM PO4, 150 mM NaCl, pH 7.4, 0.05% sodium azide. HostRabbit ReagentConc. antibody
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target
Calcitonin (Calca)
Alternative Name
Calcitonin
Background
Calcitonin is a 32-amino acid polypeptide hormone that is produced in human primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body It acts to reduce blood calcium (Ca 2+ ), opposing the effects of parathyroid hormone (PTH) Calcitonin staining can detect C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors.