CR1 / CD35 antibody

Antigen: CR1 / CD35

Clonality: Monoclonal (E11)

Host: Mouse

Reactivity: Human

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Catalog no.: ABIN337278

Additional Information

Swiss-Prot: P17927

Immunogen: Cells, Human acute monocytic leukaemia cells.

Isotype: IgG1  (Matching secondary antibodies)

Clone: E11

Description: Gene: CR1 / CD35, Standard Gene Symbol: CR1, Family: Protease, Subfamily: Serine S1, Synonyms: CR1, C3-binding protein, C3BR, C4BR, CD35, Complement component C3b/C4b receptor, Complement receptor type 1, KN

Specificity: Is a single chain cell surface glycoprotein which exists in four allotypic forms (A, B, C, D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement. Clone E11 has been reported to be suitable for use in Western Blot. Predicted Reactivities: Baboon,Monkey.

Application Details

Application Notes: Flo (1:50 - 1:100), IHC-Fr, IHC-P (10 µg/ml)

Concentration: 1 mg/ml

Purification: Protein A Column

Buffer: PBS, pH 7.4.

Storage: +4°C or -20°C, Avoid repeated freezing and thawing.

Restrictions: For Research Use only

Images

Human Kidney (formalin-fixed, paraffin-embedded) stained with CR1 antibody ABIN337278 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen.