F12 antibody
Quick Overview for F12 antibody (ABIN342144)
Target
See all F12 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with the heavy chain of human Factor XII (mw ~50000) with KD of 9.8 nM and partially blocks Factor XI I activity. The specific epitope for this antibody is located within a 20 amino acid sequence of 2.5 kD in the surface binding area of Factor XII.
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Purification
- Protein G purified
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Immunogen
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Purified human Factor XII.
Type of Immunogen: Purified protein -
Isotype
- IgG1
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Application Notes
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Approved: ELISA, WB
Usage: May be used in ELISA, Western blot, coagulation assays and for immunopurification of Factor XI I. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- F12 (Coagulation Factor XII (F12))
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Alternative Name
- F12 / Factor XII
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Background
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Name/Gene ID: F12
Subfamily: Serine S1
Family: Protease
Synonyms: F12, Beta-factor XIIa part 2, Beta-factor XIIa part 1, Coagulation factor XII, F12 deficiency, Factor XII, Factor XII deficiency, HAE3, HAEX, Hageman factor, HAF -
Gene ID
- 2161
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UniProt
- P00748
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Pathways
- Complement System
Target
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