F12 antibody (AA 486-600)

Catalog No. ABIN7147997

Product Details anti-F12 Antibody

Target: F12 (Coagulation Factor XII (F12))

Binding Specificity: AA 486-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F12 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Coagulation factor XII protein (486-600AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for F12

Target: F12 (Coagulation Factor XII (F12))

Alternative Name: F12 (F12 Products)

Synonyms: HAE3 antibody, HAEX antibody, HAF antibody, FXII antibody, coagulation factor XII antibody, coagulation factor XII (Hageman factor) antibody, F12 antibody

Background:

Background: Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

Aliases: Factor XII antibody, Beta factor XIIa part 1 antibody, Beta factor XIIa part 2 antibody, Coagulation factor XII antibody, Coagulation factor XIIa heavy chain antibody, Coagulation factor XIIa light chain antibody, F12 antibody, F12 deficiency antibody, FA12_HUMAN antibody, Factor XII deficiency antibody, HAE3 antibody, HAEX antibody, HAF antibody, HAF deficiency antibody, Hageman factor antibody

UniProt: P00748

Pathways: Complement System