GAP43 antibody (pSer41)

Catalog No. ABIN350110

This Rabbit Polyclonal antibody specifically detects GAP43 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for GAP43 antibody (pSer41) (ABIN350110)

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAP43 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GAP43 Antibody

Binding Specificity: pSer41

Purpose: Rabbit antibody to phospho S41 GAP43

Specificity: Specific for GAP-43.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide to phospho S41 of human Axonal membrane protein GAP-43 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in many species including rat mouse and zebrafish.

Isotype: IgG

Application Details

Application Notes: IHC WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications. This antibody may also recognise the unphosphorylated form.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Alternative Name: GAP43

Background: FUNCTION: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. SUBUNIT: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence. SUBCELLULAR LOCATION: Cell membrane, Peripheral membrane protein, Cytoplasmic side. Cell projection growth cone membrane, Peripheral membrane protein, Cytoplasmic side. Cell junction synapse. Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.

UniProt: P17677