NGFR antibody
Quick Overview for NGFR antibody (ABIN350707)
Target
See all NGFR AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purpose
- Mouse monoclonal antibody to rat p75NTR (MC192)
-
Specificity
- Specific for rat p75NTR.
-
Cross-Reactivity
- Rat
-
Purification
- Affinity purified
-
Immunogen
- Nerve growth factor receptor (TNFR superfamily member 16)
-
-
anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR Reactivity: Human, Rat, Mouse WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal NGFR-1964 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular) antibodyKO Validated NGFR Reactivity: Human WB, IHC, FACS, IF, IP, IC, LCI Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate, Rabbit, Cat, Ferret WB, FACS, IHC (p), ICC, IP, ICFC, MS Host: Mouse Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 2F1C2 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal rNGFR-1965 unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate IHC, Diff, StM Host: Rabbit Monoclonal NGFR-1997R unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IHC, IF, ELISA Host: Mouse Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IF, IHC (p) Host: Mouse Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human WB, FACS, IF, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
- WB IHC ELISA. A working concentration of 5-15 μg,ml is recommended. This antibody is suitable for use in paraformaldehyde fixed alcohol fixed,paraffin-embedded sections. The optimal working solution should be determined by the end user.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
-
Handling Advice
- Avoid freeze and thaw cycles.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
-
Expiry Date
- 12 months
-
-
- NGFR (Nerve Growth Factor Receptor (NGFR))
-
Alternative Name
- p75NTR
-
Background
- FUNCTION: Low affinity receptor which can bind to NGF BDNF NT-3 and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2 TRAF4 TRAF6 PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.
-
Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
Target
-
