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NGFR antibody

This Mouse Monoclonal antibody specifically detects NGFR in WB, ELISA and IHC. It exhibits reactivity toward Rat.
Catalog No. ABIN350707

Quick Overview for NGFR antibody (ABIN350707)

Target

See all NGFR Antibodies
NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity

  • 159
  • 62
  • 54
  • 29
  • 27
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  • 21
  • 11
  • 5
  • 4
  • 3
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  • 1
  • 1
Rat

Host

  • 90
  • 75
  • 4
  • 1
Mouse

Clonality

  • 94
  • 76
Monoclonal

Conjugate

  • 88
  • 14
  • 11
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NGFR antibody is un-conjugated

Application

  • 94
  • 84
  • 58
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  • 42
  • 28
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Purpose

    Mouse monoclonal antibody to rat p75NTR (MC192)

    Specificity

    Specific for rat p75NTR.

    Cross-Reactivity

    Rat

    Purification

    Affinity purified

    Immunogen

    Nerve growth factor receptor (TNFR superfamily member 16)
  • Application Notes

    WB IHC ELISA. A working concentration of 5-15 μg,ml is recommended. This antibody is suitable for use in paraformaldehyde fixed alcohol fixed,paraffin-embedded sections. The optimal working solution should be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

    Handling Advice

    Avoid freeze and thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    Expiry Date

    12 months
  • Target

    NGFR (Nerve Growth Factor Receptor (NGFR))

    Alternative Name

    p75NTR

    Background

    FUNCTION: Low affinity receptor which can bind to NGF BDNF NT-3 and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2 TRAF4 TRAF6 PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.

    Pathways

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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