ZIC1-3 antibody (C-Term)

Catalog No. ABIN351417

This anti-ZIC1-3 antibody is a Rabbit Polyclonal antibody detecting ZIC1-3 in IHC and WB. Suitable for Human.

Quick Overview for ZIC1-3 antibody (C-Term) (ABIN351417)

Target: ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-ZIC1-3 Antibody

Binding Specificity: C-Term

Purpose: Rabbit antibody to ZIC1-3

Specificity: Specific for ZIC1 2 3.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from c-terminal region of human ZIC3 (Zinc finger protein ZIC 3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat and mouse.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for ZIC1-3

Target: ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))

Alternative Name: ZIC1-3

Background: Function: Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation. Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs including asplenia or polysplenia symmetric liver intestinal malrotation and abnormal lung lobation.

UniProt: O60481