ACTH
Reactivity: Human, Rat
IF (p), IF (cc)
Host: Rabbit
Polyclonal
AbBy Fluor® 750
Application Notes
Optimal working dilutions should be determined experimentally by the investigator.
Restrictions
For Research Use only
Storage
RT
Target
ACTH
(Adrenocorticotropic hormone (ACTH))
Alternative Name
ACTH
Target Type
Hormone
Background
Adrenocorticotropin (ACTH) occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. ACTH can alter pain sensitivity. The effect of corticosteroids, like ACTH on the sensitivity to pain is an indirect one by virtue of their negative feed-back action on the hypothalamic-pituitary system.