ACTH antibody

Catalog No. ABIN7072981

The Rabbit Polyclonal anti-ACTH antibody (ABIN7072981) specifically detects ACTH in WB. The antibody is reactive with Rat and Mouse samples.

Quick Overview for ACTH antibody (ABIN7072981)

Target: ACTH (Adrenocorticotropic hormone (ACTH))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACTH Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ACTH

Application Details

Application Notes: WB (M,R) 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ACTH

Target: ACTH (Adrenocorticotropic hormone (ACTH))

Alternative Name: ACTH

Background: Pro-opiomelanocortin (POMC) is a precursor polypeptide with 266 amino acid residues. POMC is synthesized in the pituitary from the 285-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 44-amino-acid-long signal peptide sequence during translation. POMC is cleaved to give rise to multiple peptide hormones(α-MSH, ACTH, β-Endorphin and [Met]enkephalin). Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent.. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress. Its principal effects are increased production and release of cortisol by the cortex of the adrenal gland. ACTH is also related to the circadian rhythm in many organisms.

Molecular Weight: 30 kDa

Gene ID: 18976

NCBI Accession: NP_001265510

UniProt: P01193

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity