CRABP2 antibody (N-Term)
Quick Overview for CRABP2 antibody (N-Term) (ABIN356224)
Target
See all CRABP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-138, N-Term
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Specificity
- The antibody recognizes Human and Mouse CRABP2. Other species not tested.
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Characteristics
- Synonyms: CRABP-II, Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II
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Purification
- Protein-G affinity chromatography
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Immunogen
- Recombinant Human CRABP2 (1-138aa) purified from E. coli
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Isotype
- IgG2a
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Application Notes
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ELISA. Western blot (1/250-1/1,000). Immunohistochemistry on Paraffin Sections (10 μg/mL). This CRABP2 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- CRABP2 (Cellular Retinoic Acid Binding Protein 2 (CRABP2))
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Alternative Name
- CRABP2
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Background
- The cellular retinoic acid-binding protein II (CRABP-II) is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus.Synonyms: CRABP-II, Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II
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Gene ID
- 1382
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UniProt
- P29373
Target
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