MMP13 antibody (C-Term)

Catalog No. ABIN356436

The Rabbit Polyclonal anti-MMP13 antibody (ABIN356436) specifically detects MMP13 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for MMP13 antibody (C-Term) (ABIN356436)

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MMP13 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts with C-terminal domain of Matrix Metalloproteinase 13 (MMP13/Collagenase3).

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to C-terminal domain of human MMP13 - KLH conjugated.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Embedded Tissues: 50 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MMP13

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Alternative Name: MMP-13

Background: MMP13 is a Metallopeptidase M10A type protease. Metalloproteinase 13/Collagenase 3 (MMP13) was originally identified in breast carcinoma and has since been documented in a variety of tumors including chondrosarcomas, basal cell carcinoma, and malignant melanoma. In addition it has been detected in inflammatory diseases such as atherosclerosis, in wound healing, and in destructive joint diseases such OA and RA. MMP13 degrades the native helix of several types of fibrillar collagen, and extracellular matrix proteins in vitro.Synonyms: Collagenase 3, MMP13, Matrix metalloproteinase-13

Gene ID: 4322

NCBI Accession: NP_002418

UniProt: P45452