SENP6 antibody (C-Term)

Catalog No. ABIN356759

The Rabbit Polyclonal anti-SENP6 antibody is suitable to detect SENP6 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for SENP6 antibody (C-Term) (ABIN356759)

Target: SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-SENP6 Antibody

Binding Specificity: C-Term

Specificity: This antibody is specific to SENP6 (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SENP6.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SENP6

Target: SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

Alternative Name: SENP6

Background: SENP6 (SUSP1) is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. This protein does not seem to be involved in the processing of full-length SUMO proteins to their mature conjugatable forms. SENP6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. It may act preferentially on substrates containing 3 or more SUMO2 or SUMO3 moieties.Synonyms: KIAA0797, SSP1, SUMO-1-specific protease 1, SUSP1, Sentrin-specific protease 6, Sentrin/SUMO-specific protease SENP6

Gene ID: 26054, 9606

UniProt: Q9GZR1