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HNMT antibody (N-Term)

HNMT Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN356933
  • Target See all HNMT Antibodies
    HNMT (Histamine N-Methyltransferase (HNMT))
    Binding Specificity
    • 10
    • 9
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 40
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 6
    • 1
    Rabbit
    Clonality
    • 35
    • 5
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HNMT antibody is un-conjugated
    Application
    • 33
    • 20
    • 19
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects HNMT at N-term.
    Purification
    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human HNMT.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HNMT Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    HNMT (Histamine N-Methyltransferase (HNMT))
    Alternative Name
    HNMT / HMT (HNMT Products)
    Synonyms
    HMT antibody, HNMT-S1 antibody, HNMT-S2 antibody, hmt antibody, hnmt antibody, hnmt-s1 antibody, hnmt-s2 antibody, zgc:100917 antibody, HNMT antibody, 1500031F01Rik antibody, AI788969 antibody, HMT A antibody, hnmt-a antibody, hnmt-b antibody, histamine N-methyltransferase antibody, histamine N-methyltransferase S homeolog antibody, histamine N-methyltransferase-like antibody, histamine N-methyltransferase L homeolog antibody, HNMT antibody, hnmt.S antibody, hnmt antibody, Hnmt antibody, LOC100228106 antibody, hnmt.L antibody
    Background
    In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.Synonyms: Histamine N-methyltransferase
    Molecular Weight
    33295 Da
    Gene ID
    3176, 9606
    UniProt
    P50135
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