phosphodiesterase 8A (PDE8A) (Center) antibody

Antigen: phosphodiesterase 8A (PDE8A)

Synonyms: FLJ16150, HsT19550, Pde8, AI551852, RNPDE8A, PDE8A, Pde8a

Epitope: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN356970

Additional Information

Characteristics: Synonyms: Phosphodiesterase 8A, FLJ16150, HsT19550, High affinity cAMP-specific andIBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A, cAMP-specific cyclic nucleotidephosphodiesterase 8A

Alternative name: PDE8A

Gene ID: 5151

Swiss-Prot: O60658

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the Center region of human PDE8A.

Cross-Reactivity: Human

Isotype: Ig  (Matching secondary antibodies)

Description: PDE8A plays a role in signal transduction by regulating the intracellular concentration ofcyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may beinvolved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulationof germ cell development.

Specificity: This antibody detects PDE8A at Center. Species: Human. Others not tested. Add. Information: Molecular weight: 93173 Da

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: PBS with 0.09% (W/V) sodium azide

Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only