ALDH1A1 antibody (Center)
Quick Overview for ALDH1A1 antibody (Center) (ABIN356973)
Target
See all ALDH1A1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Center
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Specificity
- This antibody detects ALDH1A1 at Center.
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Purification
- Purified
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Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ALDH1A1.
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Isotype
- Ig Fraction
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Application Notes
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunofluorescence 1: 10 - 1: 50. Immunohistochemistry 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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Alternative Name
- ALDH1
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Background
- ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.Synonyms: ALDC, ALDH-E1, ALDH1A1, ALHDII, Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, PUMB1, RALDH1, Retinal dehydrogenase 1
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Molecular Weight
- 54731 Da
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Gene ID
- 216, 9606
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UniProt
- P00352
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Pathways
- Dopaminergic Neurogenesis
Target
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