CBX8 antibody (C-Term)

Catalog No. ABIN357753

The Rabbit Polyclonal anti-CBX8 antibody (ABIN357753) specifically detects CBX8 in WB, IHC (p) and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CBX8 antibody (C-Term) (ABIN357753)

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CBX8 Antibody

Binding Specificity: C-Term

Specificity: This antibody is specific to CBX8 (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CBX8.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8

Background: Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.Synonyms: Chromobox protein homolog 8, PC3, Polycomb 3 homolog, RC1, Rectachrome 1

Molecular Weight: 43437 Da

Gene ID: 57332, 9606

UniProt: Q9HC52