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Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody

Details for Product No. ABIN357898, Supplier: Login to see
Antigen
  • ADCY2
  • mKIAA1060
  • AC2
  • HBAC2
Alternatives
anti-Human Adenylate Cyclase 2 (Brain) antibody for Enzyme Immunoassay
Epitope
C-Term
5
4
3
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
28
6
5
1
Host
Rabbit
26
3
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
24
12
4
4
3
2
2
2
1
1
1
1
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ADCY2.
Isotype Ig
Specificity This antibody detects Adenylate Cyclase 2 (ADCY2) (C-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Adenylate Cyclase Type 2 (ADCY2 Antibody Abstract)
Background ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.Synonyms: ADCY2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, KIAA1060
Molecular Weight 123603 Da
Gene ID 108, 9606
UniProt Q08462
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody (ABIN357898) anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody
 image for anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody (ABIN357898) anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody (Image 2)
Background publications Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Ludwig, Seuwen: "Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms." in: Journal of receptor and signal transduction research, Vol. 22, Issue 1-4, pp. 79-110, 2002 (PubMed).