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Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody

Details for Product No. ABIN357898
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Antigen
Synonyms ADCY2, mKIAA1060, AC2, HBAC2
Epitope
C-Term
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(28), (13), (13), (12), (12), (12), (1)
Host
Rabbit
(27), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(19), (10), (7), (5), (2), (1), (1), (1)
Pubmed 2 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN357898
357.50 $
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ADCY2.
Specificity This antibody detects Adenylate Cyclase 2 (ADCY2) (C-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Adenylate cyclase type 2
Background ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
Alternate names: ADCY2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, KIAA1060
Molecular Weight 123603 Da
Gene ID 108
NCBI Accession 9606
UniProt Q08462
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody
anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody (2) anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody (Image 2)
Background publications Ludwig, Seuwen: "Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms." in: Journal of receptor and signal transduction research, Vol. 22, Issue 1-4, pp. 79-110, 2002 (PubMed).

Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Validation Images
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