CREB3L1 antibody (C-Term)

Catalog No. ABIN358719

The Rabbit Polyclonal anti-CREB3L1 antibody (ABIN358719) specifically detects CREB3L1 in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for CREB3L1 antibody (C-Term) (ABIN358719)

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CREB3L1 Antibody

Binding Specificity: AA 490-519, C-Term

Specificity: This antibody detects OASIS at C-term.

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490~519 amino acids from the C-terminal region of Human OASIS.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Alternative Name: CREB3L1 / OASIS

Background: OASIS is a putative CREB/ATF family transcription factor with a putative C-terminal hydrophobic transmembrane domain. It can activate transcription through box-B elements but not through CRE of somatostatin. Shortening of the OASIS transmembrane domain results in a significant increase in transcriptional activity and changes its subcellular localization from the endoplasmic reticulum to the nucleus.Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 1, Old astrocyte specifically-induced, PSEC0238, cAMP-responsive element-binding protein 3-like protein 1

Gene ID: 90993, 9606

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding