PARP6 antibody (C-Term)

Catalog No. ABIN358806

The Rabbit Polyclonal anti-PARP6 antibody (ABIN358806) specifically detects PARP6 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for PARP6 antibody (C-Term) (ABIN358806)

Target: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PARP6 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to PARP6.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PARP6.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PARP6

Target: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Alternative Name: PARP6

Background: Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.Synonyms: PARP-6, Poly [ADP-ribose] polymerase 6

Gene ID: 56965, 9606

UniProt: Q2NL67